Following the full-scale outbreak of the War of Resistance Against Japanese Aggression, fuel became critically scarce in the Great Rear Area. To implement the national defense strategy of "using alcohol to replace gasoline," the Zizhong Alcohol Factory was officially established in 1938 in Yinshan Town, Zizhong County, Sichuan Province, on the banks of the Tuo River.

The factory's architectural design was personally led by the renowned modern Huagai Architectural Office and the master architect Tong Jun. Under conditions of extreme material scarcity during the war, Tong Jun adopted a modern pragmatic architectural style, discarding elaborate surface decorations. By integrating the actual topography of Yinshan Town, he designed modern industrial workshops with scientific layouts and robust structures. These buildings not only fully met the industrial production needs of the time but also became typical representatives of modern industrial architecture in China's Great Rear Area.

Leveraging the abundant molasses—a waste liquid from sugarcane sugar production—available in the Neijiang region, the Zizhong Alcohol Factory successfully achieved large-scale mass production of anhydrous alcohol within these newly constructed workshops. The high-purity power alcohol produced by the factory was continuously transported in large quantities to the anti-Japanese front lines, effectively filling the shortage of fuel for automobiles and even aircraft, thereby providing crucial energy support for military logistics during the War of Resistance.